Fast Dissolving Thin Films

Many pharmaceutical dosages are administrated in the form of pills, granules, powders, and liquids. Generally a pill design is for swallowing intact or chewing to deliver a precise dosage of medication to patients. The pills, which include tablets and capsules, are able to retain their shapes under moderate pressure. However, some patients, particularly pediatric and geriatric patients, have difficulty swallowing or chewing solid dosage forms. Many pediatric and geriatric patients are unwilling to take these solid preparations due to fear of choking. Likewise, many pets have difficulty and / or strong resistance to taking medication in a pill form.

In order to assist these patients and pets, MIGAMI acquired a proprietary patented technology that is a thin, flexible and quick-dissolving film. The film is placed on the top or the floor of the tongue. Instantly wet by saliva, the film rapidly hydrates and adheres onto the site of application. It then disintegrates and dissolves to release the active agent for local and / or systemic absorption. This fast-dissolving delivery system has the following competitive advantages - fast absorption, convenient dosing, no risk of choking, enhanced stability, improved patient compliance, transportability, ease of handling and administration, no water necessary for application, and a pleasant taste. The thin film products also can be designed to dissolve at varying rates of speed.